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Today, Opera becomes the first major browser after Apple’s Safari to introduce support for the Touch Bar in a final version. How you can browse with Touch Bar Opera.B. Gerard- LB8. TG in ZO- Noorwegen; S=9. Lau- OK/PD9. RF in Tsjechi. Elke 5 jaar (wanneer het jaartal deelbaar is door 5) organiseert de VERON samen met de VRZA op 4 mei een herdenkingsbijeenkomst. In de tussenliggende jaren wordt er ook een herdenking gehouden, maar deze is kleiner en persoonlijker van opzet. Herdenking gevallen radioamateurs? De organisatie van deze herdenking lag in handen van Radio Club ’t Gooi, waarbij Ren. Na de 2 minuten stilte werden er bloemen bij het monument gelegd door Bernard Grijpstra namens KPN, Rene Verhaaf PE1. GDP namens de VERON en Chris van den Berg PA3. CRX namens het VERON Hoofdbestuur. De VERON bedankt KPN voor het faciliteren van deze herdenking. BRON: https: //www. NAM- MIDDENGOLF IN NEDERLAND4- 5- 1. Kort AM nieuws = Op AM 8. Huissen wordt al geruime tijd niet meer het programma HOTRADIO Hits uitgezonden maar non- stop muziek uit de jaren 8. Wereldstad test af en toe ook op AM 1. Hz vanuit Rotterdam Hoogvliet.= Vanuit Rijswijk in Noord- Brabant zendt sinds 2 april Radio Koekoek uit op 1. Hz op zondagen tussen 1. Klik op de foto rechts voor een groter exemplaar van de antenne.= Door problemen met de antenne is Memories 1. AM uit Geffen tijdelijk uit de lucht. Voor een overzicht van alle omroepen die op AM uitzenden en vergunning hebben om te mogen gaan uitzenden kijk hier. BRON: http: //radio- tv- nederland. NGrote prijsverschillen inkoopsites gebruikte smartphonesvrijdag 5 mei 2. De verschillen komen tot uiting in onder meer de prijzen die worden betaald voor gebruikte telefoons, de voorwaarden en de afhandeling van het inkooptraject. Bij onenigheid over de staat van het toestel of een tegenvallend bod is er bovendien soms onduidelijkheid over of het toestel teruggestuurd wordt. De consumentenorganisatie heeft zes inkoopsites doorgelicht met een prijzenscan en praktijkproef. Het gaat om sites die hoog staan in de zoekresultaten van Google: GSMLoket, Recycle. Michael, Rebuy, Verkoopjetelefoon, We. Buy. It en Zonzoo. Vooral toestellen uit hogere prijsklassen kunnen nog een redelijke prijs opleveren voor de verkopende consument. De opbrengst daalt snel bij goedkopere smartphones. Ook zijn er soms forse verschillen tussen inkoopprijzen voor hetzelfde toestel, zo blijkt uit de prijzenscan. Voor een Samsung Galaxy S6 in goede staat bijvoorbeeld biedt Recycle. Michael 2. 22 euro, tegen 1. Rebuy. Recycle. Michael heeft bij 6 van de 1. Zonzoo en Verkoopjetelefoon hebben doorgaans het laagste maximumbod. Het gemiddelde prijsverschil tussen het laagste en het hoogste maximumbod bedroeg 3. De praktijkproef bracht onder meer aan het licht dat inkoopsites het bod na inspectie van het toestel geregeld naar beneden bijstellen. Dit gebeurde bij zeven van de twaalf toestellen die de Consumentenbond instuurde. De afhandeling van de verkoop is soms vlekkeloos, soms zijn er problemen of duurt het lang. De Consumentenbond noemt het verder opmerkelijk dat We. Buy. It en Zonzoo in hun voorwaarden zeggen het toestel niet terug te sturen als consumenten niet tevreden zijn met het bod, maar dat in de praktijk wel doen. Alleen Verkoopjetelefoon. De Consumentenbond heeft het bedrijf laten weten dat het goed moeten aangeven dat consumenten een smartphone niet terugkrijgen bij een geschil over de staat van het toestel. BRON: https: //www. NTele. 2: Roam- like- at- Home vanaf 8 juni geldigvrijdag 5 mei 2. Vanaf die dag krijgen Nederlandse abonnees bij roaming in de EU volledig de beschikking over de eigen bundel voor bellen, sms en mobiel internet. Als de bundel verbruikt is, biedt Tele. De tarieven zijn in Nederland en de EU gelijkgetrokken. Tele. 2 voldoet op tijd aan de Europese regels, 1. Ook Vodafone, KPN en T- Mobile hebben hun proposities al aangepast, met 1 juni als startdatum. BRON: https: //www. NNieuwe gentherapie valt 'commandocentrum van kanker' aan. Caroline Kraaijvanger. Experimenten met muizen die aan een agressieve vorm van prostaat- of leverkanker lijden, zijn zeer veelbelovend. Dat maken wetenschappers van de universiteit van Pittsburgh bekend in het blad Nature Biotechnology. In hun paper beschrijven ze hoe ze kanker met behulp van CRISPR (zie kader) de pas afsnijden. CRISPRCRISPR is een genome editing- methode die onderzoekers in staat stelt om genen te controleren. Zo kunnen ze de methode gebruiken om genen uit te schakelen of ongewenst genetisch materiaal te vervangen door een wenselijke DNA- sequentie. Onderstaand filmpje legt in detail uit hoe de methode – die bedacht is door moeder natuur zelf – werkt. VIDEO - Genome Editing with CRISPR- Cas. E4. E- O8. Fusie- genen. Het nieuwe onderzoek richt zich op zogenoemde fusie- genen. Dit zijn genen die ontstaan als twee afzonderlijke genen hun krachten bundelen en een abnormaal eiwit vormen dat kanker kan veroorzaken of promoten. Tijdens dit onderzoek richtten de wetenschappers zich op het fusie- gen MAN2. A1- FER. Dit gen is tijdens eerder onderzoek in verband gebracht met agressieve vormen van lever- , long- , prostaat- en eierstokkanker. CRISPR in actie. Het fusie- gen in kwestie heeft een unieke DNA- sequentie waaraan het te herkennen is. De onderzoekers spoorden de genen aan de hand van die DNA- sequentie op en gebruikten vervolgens virussen om het gemuteerde DNA van de fusie- genen weg te knippen en het te vervangen door een gen dat kankercellen doodt. Omdat het fusie- gen alleen aanwezig is in kankercellen en niet in gezonde cellen, heeft de behandeling alleen gevolgen voor de kankercellen en dus veel minder nare bijwerkingen dan bestaande behandelingen tegen kanker, zoals bijvoorbeeld chemotherapie (dat geen onderscheid maakt tussen gezonde cellen of kankercellen). Muismodellen. Experimenten met muizen tonen aan dat de aanpak van de onderzoekers veelbelovend is. De onderzoekers stopten menselijke prostaat- en leverkankercellen in de lichamen van de muizen. Vervolgens pasten ze bij de helft van de muizen het fusie- gen in de kankercellen aan. Hierdoor krompen de tumoren met dertig procent. Geen van de muizen kreeg te maken met uitzaaiingen en aan het eind van de acht weken durende observatieperiode leefden de muizen allemaal nog. Heel anders was het in de controlegroep. Deze muizen hadden ook kankercellen in hun lichaam, maar bij hen werd een fusie- gen dat niet in de tumoren aanwezig was, aangepast. De tumoren van deze muizen werden bijna 4. Nieuwe aanpak. Het onderzoek kan wel eens leiden tot een compleet nieuwe manier om kanker te bestrijden. Een veelvoorkomend probleem dat de effectiviteit van chemotherapie aantast, is dat kankercellen evolueren en nieuwe mutaties genereren. Met genome editing kunnen onderzoekers in zo’n geval simpelweg de focus verleggen en die nieuwe mutaties aan gaan vallen. De onderzoekers zijn zeker nog niet klaar met de fusie- genen. In deze studie is onder de bestudeerde muizen slechts sprake van een gedeeltelijke remissie. De wetenschappers willen uitzoeken of het met deze aanpak ook mogelijk is om de ziekte helemaal uit te roeien. BRON: www. scientias. NGame of Thrones bij mieren: daar komen feromonen bij kijken. Caroline Kraaijvanger. Wetenschappers hebben ontdekt dat larven die azen op de troon een . En kan de kolonie vervolgens – indien nodig – actie ondernemen. Dat hebben Amerikaanse onderzoekers ontdekt toen ze de mieren die behoren tot de soort Harpegnathos saltator bestudeerden. Timing. Bij deze Indiase soort is het zo dat lang niet elke larve met koninklijke ambities daadwerkelijk een koningin wordt. Of de koninklijke ambities werkelijkheid worden, is afhankelijk van de timing van de larve. Als een larve met koninklijke ambities tegen de tijd dat de eerste zomerregens zich aandienen, het levenslicht ziet, is er niks aan de hand. De larven worden verzorgd en groeien uit tot koninginnen. Eenmaal volwassen gaan ze op pad, op zoek naar een mannetje om mee te paren. Als dat gelukt is, richten de koninginnen vervolgens hun eigen kolonie op. Foute timing. Maar stel nu dat zo’n larve met koninklijke ambities ergens halverwege de winter geboren wordt. Dan kan deze onmogelijk een partner vinden en dus ook geen nieuwe kolonie stichten. Aan zo’n koningin – die alleen maar profiteert van de kolonie – hebben de mieren natuurlijk niks. En dus brengen ze de larven die koninklijke ambities hebben, maar op het verkeerde moment het levenslicht zien, op andere gedachten. Ze gaan de larve bijten (zie de filmpjes hieronder). En die stress zorgt ervoor dat deze haar ambities laat varen en een werker in plaats van een koningin wordt. VIDEO - attacking larvae (Converted): https: //vimeo. Feromonen. Maar hoe weet de kolonie dat een larve koninklijke ambities heeft? Daar zijn onderzoekers nu uit. Een nieuwe studie toont aan dat de larven een . Het waslaagje van grote larven – die duidelijk uit zouden groeien tot koninginnen – was heel anders dan dat van kleinere larven die werkers zouden worden. Tijdens experimenten smeerden de onderzoekers een beetje was van de rug van een larve met koninklijke ambities op de huid van een larve die uit zou groeien tot een werker. Daarop gingen de werkers de laatstgenoemde larve behandelen alsof het een prinses was. En wanneer onderzoekers larven die uit zouden groeien tot werkers behandelden met een hormoon dat ervoor zorgt dat larven koninklijke ambities krijgen, gingen die werker- larven het prinses- feromoon produceren. Dat gebeurde zelfs wanneer de onderzoekers het hormoon gaven aan mannelijke werker- larven. Mieren moeten een manier hebben om zich ervan te verzekeren dat ze voldoende werkers in hun kolonie hebben, anders zouden alle larven koninginnen worden en de samenleving ineenstorten.”BRON: www. NEpsilon Eridani- stelsel lijkt op ons zonnestelseldinsdag 2 mei 2. Iowa State University. Human Knowledge: Foundations and Limits. Human Knowledge: Foundations and Limitshttp: //humanknowledge. Does divine. or supernatural agency exist? Is the future already. What is right. and wrong? Is the world good. Are humans good or evil? What beings. have what rights? What are the limits. Could a machine. think? What laws. it? Why is the universe this way? 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